Our mission is centered on a simple yet profound principle: the strategic utilization of bioactive gases—including Oxygen (O2), Hydrogen (H2), Carbon Dioxide (CO2), and Nitric Oxide (NO)—which are fundamental elements of life and health. By leveraging transdermal gas absorption, these essential molecules permeate the skin at a near-constant rate to enter systemic circulation, eliciting both localized and systemic therapeutic effects. We believe that the principles of Gas Microenvironment Management (GMM) can fundamentally enhance human health. Our objective is to innovate products that optimize microenvironment management for superior health outcomes.

The Cellular Regenerative Medical Gas (CRMG) Research Center focuses on the following key research areas:

1. Fundamental Interactions between Medical Gases and Human Health Investigating the relationships between medical gases—including reactive oxygen species (ROS), hypoxia, oxygen, nitric oxide, singlet oxygen, hydrogen peroxide, hydrogen sulfide, nitrogen oxides, argon, and helium—and their profound impacts on human survival, health maintenance, and disease pathophysiology.

2. Technological Innovations in Therapy and Delivery Exploring the applications of medical gases in cutting-edge technologies such as Photodynamic Therapy (PDT), advanced drug delivery systems, graphene oxide/reduced graphene oxide, antioxidants, Photothermal Therapy (PTT), Sonodynamic Therapy (SDT), superparamagnetic iron oxide nanoparticles (SPIONs), and strategies for oxygen generation to counteract tumor hypoxia.

3. Basic Medical Research: Mechanisms and Pathways Elucidating the roles and molecular mechanisms of medical gases across diverse fields, including biomaterials, pharmacology, biochemistry, mitochondrial function, ferroptosis, cellular senescence, antimicrobial action, apoptosis, angiogenesis, immunotherapy, drug resistance, oxidative stress, and exosome biology.

4. Clinical Applications and Translational Medicine Researching the efficacy and mechanisms of medical gases in clinical disciplines such as oncology (specifically the tumor microenvironment), medical imaging, inflammation management, wound healing, high-altitude medicine, hyperbaric and undersea medicine, anesthesiology, interventional radiology, microbiology, cardiology, and neuroscience.